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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: J Nanomed Nanotechnol. 2015 Oct 1;6(Suppl 6):006. doi: 10.4172/2157-7439.S6-006

Figure 5.

Figure 5

Serum proinflammatory cytokine concentrations following IT instillation of AgNP or AgAc. Serum concentration of proinflammatory cytokines 1 day and 7 days after IT instillation. Cytokines IL-1β (A), IL-6 (C), IL-18 (D), and TNFα (E) were elevated compared to citrate vehicle 1 day following IT instillation. At 7 days following instillation only TNFα (H) remained elevated above vehicle. b denotes statistical significance from vehicle. c denotes difference compared to 1mg/ml AgAc p<0.05 by t-test, Data are reported as mean ± SEM with n=4–5.