Table 1. Patient characteristics.
| Engage N = 1405 | Ensure N = 389 | Trust N = 639 | Total N = 2433 | |
|---|---|---|---|---|
| Age (years), mean (SD) | 31.5 (3.3) | 31.0 (3.1) | 32.9 (3.6) | 31.8 (3.4) |
| BMI (kg/m2), mean (SD)a | 24.8 (2.7) | 20.6 (1.5) | 24.2 (2.4) | 24 (2.9) |
| AFC, mean (SD)b | 12.4 (4.5) | 11.1 (4.4) | 10.8 (4.7) | 11.8 (4.6) |
| Dose reductions of rFSH from day 8 onwards, %c | 46.1 | 37.1 | 90.3 | 56.7 |
| Oocytes retrieved, mean (SD) | 13.5 (7.4) | 12.4 (6.9) | 12.3 (7.0) | 13.0 (7.2) |
| Fertility characteristics | ||||
| Primary infertility, % | 53.0 | 61.4 | 57.0 | 55.4 |
| Duration of infertility (years), mean (SD)d | 3.3 (2.4) | 3.2 (2.2) | 3.7 (2.9) | 3.4 (2.5) |
| Dose of hCG administerede | ||||
| 10,000 IU, % | 83.2 | 83.8 | 66.4 | 78.8 |
| 5000 IU, % | 16.8 | 16.2 | 8.8 | 14.6 |
| rhCG 250 μg, % | 0.0 | 0.0 | 24.9 | 6.5 |
| Day of hCG | ||||
| Follicles ≥11 mm, mean (SD) | 14.9 (6.6) | 14.2 (6.4) | 14.5 (6.5) | 14.7 (6.5) |
| Serum E2, pmol/L, mean (SD) | 5323.1 (3241.4) | 5222.7 (3272.9) | 5595.0 (3393.0) | 5378.5 (3288.3) |
| Serum FSH, IU/L, mean (SD) | 12.1 (3.1) | 11.6 (3.0) | 13.6 (3.7) | 12.4 (3.3) |
| Serum LH, IU/L, mean (SD) | 1.6 (1.7) | 1.5 (1.7) | 1.5 (1.9) | 1.6 (1.8) |
| Serum P, nmol/L, mean (SD) | 3.1 (1.8) | 2.5 (1.5) | 4.1 (23.4) | 3.3 (12.1) |
a6 missing body mass index (BMI) values;
b64 missing antral follicle count (AFC);
cbased on 2129 patients receiving rFSH from day 8 onwards;
d2 missing durations;
e3 other.