Figure 9.

Drug distribution in plasma, tumor, and main tissues including heart, liver, spleen, lung, kidney, and stomach in tumor-bearing mice after oral administration of 5-fluorouracil (5-FU) hollow microspheres as a test formulation and its solid microspheres and powder as controls in the sodium carboxymethyl cellulose suspension form at a dose of 72 mg/kg body weight.

Notes: These values are arithmetic mean ± standard deviation. Plasma, ng/mL; tumor and main tissues, ng/g.

Abbreviation: h, hours.