Table 1.

The effect of Span 80 concentration in the liquid paraffin on particle size, drug loading amount, and production yield of 5-fluorouracil hollow microspheres^a

Span 80 concentration (%)	Particle size distribution			Drug loading (%)	Production yield (%)
	<450 µm (%)	450–600 µm (%)	>600 µm (%)
0.5	9.1±0.4	25.6±2.5	63.3±3.6	18.4±1.1	38.9±1.0
1.0	14.2±0.7	27.2±2.4	58.6±2.9	23.5±1.2	48.4±1.3
1.5	19.5±0.5	70.6±4.7	9.9±1.0	27.6±1.4	67.5±1.6
2.0	58.1±3.8	33.6±2.2	8.3±0.6	21.3±1.1	60.2±1.9

Note:

^aMean ± standard deviation.