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. 2016 Mar 7;11(3):e0150909. doi: 10.1371/journal.pone.0150909

Table 1. Detection of bacteria, inflamed area and macrophage infiltration in the lungs of mice infected with Waddlia chondrophila.

Day (n) 0 (8) 1 (8) 3 (6) 7 (6) 10 (6)
Presence of Waddlia chondrophila* 0.75 2.7 3.8 1.7 0.7
Inflamed area (%)** 18 34 44 57.5 33
Macrophage infiltration*** 0 0 1.6 1.8 1

* The detection of W. chondrophila within cells was scored on a scale from 0 (no Waddlia) to 4 (strong presence of Waddlia).

** Inflamed area is expressed as the percentage of total lung area.

*** Macrophage infiltration was scored on a scale from 0 (no infiltration) to 3 (strong infiltration).

At day 3, neither macrophage infiltration and nor W. chondrophila were detected in mock controls (n = 6), whereas focal inflammation was observed in one third of the animals.