Table 1. Detection of bacteria, inflamed area and macrophage infiltration in the lungs of mice infected with Waddlia chondrophila.
Day (n) | 0 (8) | 1 (8) | 3 (6) | 7 (6) | 10 (6) |
---|---|---|---|---|---|
Presence of Waddlia chondrophila* | 0.75 | 2.7 | 3.8 | 1.7 | 0.7 |
Inflamed area (%)** | 18 | 34 | 44 | 57.5 | 33 |
Macrophage infiltration*** | 0 | 0 | 1.6 | 1.8 | 1 |
* The detection of W. chondrophila within cells was scored on a scale from 0 (no Waddlia) to 4 (strong presence of Waddlia).
** Inflamed area is expressed as the percentage of total lung area.
*** Macrophage infiltration was scored on a scale from 0 (no infiltration) to 3 (strong infiltration).
At day 3, neither macrophage infiltration and nor W. chondrophila were detected in mock controls (n = 6), whereas focal inflammation was observed in one third of the animals.