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. 2016 Mar 7;11(3):e0150826. doi: 10.1371/journal.pone.0150826

Table 1. Patient characteristics.

Data are presented as medians (interquartile range).

KT Patients (n = 222) No Rejection (n = 192) (86%) Early Rejection (n = 30) (14%) P
Age recipient 57 (46–64) 55 (47–63) 0.60
Age Donor 52 (40–62) 58 (50–65) 0.024
Male gender recipient 118 (61%) 14 (63%) 0.84
Male gender donor 94 (49%) 13 (43%) 0.57
CMV-seropositivity recipient 118 (61%) 15 (50%) 0.23
CMV-serostatus donor/recipient
-/- 42 (22%) 10 (33%) 0.17
-/+ 38 (20%) 5 (17%) 0.69
+/- 32 (17%) 5 (17%) 1.00
+/+ 80 (42%) 10 (33%) 0.39
Anti-CMV IgG titer recipient (AU/mL) 65 (42–105) 58 (47–86) 0.75
Mismatch HLA class I 2 (2–3) 3 (2–3) 0.15
Mismatch HLA class II 1 (1–2) 1 (1–2) 0.31
Mismatch HLA class I and II 4 (3–5) 4 (3–5) 0.11
PRA current (%) 0 (0–4) 0 (0–4) 0.52
PRA historic (%) 4 (0–4) 4 (0–29) 0.039
Amount of KT 1 (1–1) 1 (1–1) 0.63
Warm ischemia time 20 (16–24) 21 (16–25) 0.69
Cause of CKD
Nephrosclerosis/atherosclerosis/hypertension 44 (23%) 7 (23%) 0.96
Primary glomerulopathies 26 (14%) 4 (13%) 1.00
Diabetes 41 (21%) 2 (7%) 0.06
Urinary tract infections/stones 5 (3%) 1 (3%) 0.59
Reflux nephropathy 9 (5%) 1 (0%) 1.00
Polycystic Kidney Disease 33 (17%) 7 (23%) 0.42
Other 26 (14%) 5 (17%) 0.58
Unknown 8 (4%) 3 (10%) 0.17
Pre-emptive KT 75 (39%) 17 (57%) 0.07
Genetically-related KT 82 (43%) 6 (20%) 0.018
Acute rejection type
Cellular rejection 25 (83%)
Antibody-mediated rejection 1 (3%)
Mixed rejection 4 (13%)