. 2016 Mar 7;11(3):e0148496. doi: 10.1371/journal.pone.0148496

Table 3. Mean values of each sleep variable for each study.

Studies included in the meta-analysis

Study

Arzt et al 2010 [21]: AHI<5

Arzt et al 2010 [21]: 5≤AHI<15

Arzt et al 2010 [21]: AHI≥15

Terzoudi et al 2009 [26]

Gottselig et al 2002 [27]

Müller et al 2002 [28]

Bassetti and Aldrich 2001[29]

Santamaria et al 2000 [30]

Mohesenin and Valor 1995 [33]

Hudgel et al 1993 [34]

Giubilei et al 1992 [32]_ ACUTE

Giubilei et al 1992 [32]_ AFTER 3 WEEKS

Sleep continuity

TST SG

10 studies

354,0±12,0

367,0±11,0

322,0±17,0

242,4±93,6

402,6±17,1

388,0±75,0

246,2±14,6

243,2±75,9

227,0±35,0

100,0±12,0

416,8±128,8

403,9±96,6

TST CG

10 studies

384,0±2,0

382,0±5,0

359,0±7,0

299,0±51,1

425,9±11,2

416,0±48,0

304,0±10,9

334,7±65,7

271,0±26,0

113,0±16,0

397,5±68,7

SEI SG

6 studies

76,0±2,0

76,9±2,1

70,5±3,1

75,3±17,8

78,7±2,6

76,0±10,0

69,1±2,7

SEI CG

6 studies

84,3±0,4

83,6±0,9

79,5±1,3

87,6±7,9

88,3±2,4

86,0±8,0

78,4±2,5

SOL SG

7 studies

20,7±3,0

16,6±3,6

25,6±7,4

42,2±42,5

21,7± 2,6

33,0±31,0

37,7±11,1

21,40±28,9

13,0±5,0

SOL CG

7 studies

13,0±0,6

13,2±2,0

11,7±1,1

27,2±11,2

26,7±4,7

28,0±17,0

29,5± 6,4

16,4±14,5

26,0±4,0

WASOmin SG

3 studies

105,5±13,6

112,0±53,0

74,2±48,3

WASOmin CG

3 studies

50,4±12,0

60,0±38,0

51,1± 35,0

WASO% SG

2 studies

24,8±17,8

42,0±9,0

WASO% SG

2 studies

12,4±7,8

26,0±4,0

NA SG1

1 study

31,3±16,7

17,8±9,9

NA SG1

1 study

8,1±2,5

Sleep architecture

S1min SG

2 studies

60,1±6,4

66,0±31,0

S1min CG

2 studies

62,7±8,0

58,0±24,0

S1% SG

4 studies

7,2±7,3

23,2±2,7

9,5± 5,9

12,0±3,0

S1% CG

4 studies

6,6±2,2

18,7±2,0

8,0± 4,9

8,0±1,0

S2min SG

2 studies

246,9±14,6

223,0±60,0

S2min CG

2 studies

243,0±11,2

232,0±28,0

S2% SG

4 studies

53,2±18,3

25,1±3,2

29,3± 14,4

36,0±6,0

S2% CG

4 studies

58,0±4,7

34,9±9,2

41,6± 19,2

45,0±3,0

SWSmin SG

2 studies

31,4±5,0

34,0±32,0

SWSmin CG

2 studies

39,1±9,3

45,0±34,0

SWS% SG

5 studies

12,0±1,4

10,5±1,5

10,9±2,1

6,4±5,8

1,6±0,5

24,2± 16,1

4,0±2,0

SWS% CG

5 studies

14,5±0,4

12,4±0,7

11,2±1,0

10,4±2,5

5,2±1,8

19,5± 12,5

9,0±2,0

REMmin SG

3 studies

64,2±6,0

66,0±35,0

8,3±16,3

71,2±25,0

REMmin CG

3 studies

81,1±6,0

82,0±210

68,5±36,6

REM% SG

5 studies

16,9±1,1

19,0±1,0

13,9±0,6

8,1±8,8

9,9±1,4

19,1± 6,6

7,0±3,0

REM% CG

5 studies

19,2±0,2

18,1±0,5

13,9±1,9

12,1±4,1

13,2±1,6

18,5± 8,4

14,0±2,0

REML SG

4 studies

114,5±74,7

92,0±65,0

91,2±13,5

62,8± 60,2

REML CG

4 studies

136,1±50,0

95,0±62,0

72,0±8,3

81,9± 63,3

REMD SG

1 study

0,09±0,01

REMD CG

1 study

0,09±0,03

AI SG

1 study

64,0±16,0

AI CG

1 study

20,0±3,0

Power Spectral Analysis

n_spindles/sigma activity SG

3 studies

8,4±4,6 (sigma 12,25–16,0 Hz)

68,9±21,6 (n_spindles)

26,1±29,1 (n_spindles)

n_spindles/sigma activity CG

3 studies

10,6±5,4 (sigma 12,25–16,0 Hz)

95,2±30,2 (n_spindles)

39,8±23,5 (n_spindles)

Delta 1 (0,75–2,0 Hz) SG

1 study

185±86

Delta 1 (0,75–2,0 Hz) CG

1 study

183±114

Delta 2 (0,75–4,5 Hz) SG

1 study

230±97

Delta 2 (0,75–4,5 Hz) CG

1 study

239±142

Theta (4,75–8,0 Hz) SG

1 study

29,8±23,0

Theta (4,75–8,0 Hz) CG

1 study

30,2±16,8

Alpha (8,25–12,0 Hz) SG

1 study

17,7±10,8

Alpha (8,25–12,0 Hz) CG

1 study

20,0±11,1

Daytime functioning

ESS SG

2 studies

9,3±0,3

2 studies

5,6±0,5

Other variables

AHI SG

4 studies

1,8±0,2

8,9±0,4

30,3±3,3

25,0±7,2

44,0±12,0

AHI CG

4 studies

1,2±0,1

9,0±0,2

33,1±1,8

16,7±3,3

12,0±7,0

PLMI SG

1 study

15,2±4,5

PLMI CG

1 study

9,0±3,0

Studies excluded in the meta-analysis (but included in systematic review)

Study

Coelho et al 2010 [22]

Siccoli et al 2008 [25] ACUTE (means and ranges)

Siccoli et al 2008 [25] RECOVERY (means and ranges)

Bliwise et al 2002 [23] PARKINSON

Bliwise et al 2002 [23] ALZHEIMER

Vock et al 2002 [31] ACUTE (means and ranges)

Vock et al 2002 [31] MORE CHRONIC (means and ranges)

Pinto et al. 2000 [35]

Yokoyama et al 1996 [24]

Sleep continuity

TST SG

395(221–568)

461(406–514)

327,2±95,6

390(221–568)

415(302–514)

TST CG

411(380–451)

313,3±86,1

255,4±94,8

413(352–493)

SEI SG

66,7 ±3,3

81(49–96)

94(88–98)

67,8±20,7

76(49–97)

92(63–98)

SEI CG

69,2 ±3,1

88(80–96)

70,5±16,7

55,5±23,8

88(71–98)

SOL SG

25(3–55)

23(2–45)

16,6±26,4

23(10–152)

23(1–51)

SOL CG

20(17–23)

31,6±29,6

45,2±70,0

23(8–65)

WASOmin SG

91(13–229)

27(5–56)

133(13–229)

29(5–188)

WASOmin CG

50(9–93)

52(9–129)

WASO% SG

WASO%CG

NA SG

Sleep architecture

S1min SG

50(15–107)

64(13–197)

52(15–105)

52(13–110)

S1min CG

65(33–117)

63(20–117)

S1% SG

S1% CG

S2min SG

282(142–425)

269(200–327)

231(142–425)

253(156–327)

S2min CG

227(209–253)

236(191–269)

S2% SG

S2% CG

SWSmin SG

37(0–141)

36(0–124)

32(0–141)

21(1–94)

SWSmin CG

35(10–67)

28(1–89)

SWS% SG

SWS% CG

REMmin SG

73(14–103)

92(52–149)

69(14–107)

69(32–149)

REMmin CG

85(67–100)

88(46–108)

REM% SG

12,3 ± 1,5

9,1±6,8

REM% CG

13,4 ± 1,4

17,1±10,0

14,3±11,1

REML SG

190,2±121,9

94(34–479)

99(46–218)

REML CG

113,6±90,2

75,0±78,9

61(47–201)

REMD SG

REMD CG

AI SG

AI CG

Power Spectral Analysis

PSA

results presented graphical^#

Daytime functioning

ESS SG

ESS CG

Other variables

AHI SG

14,4 ± 2,7

19,4±22,5(RDI)

AHI CG

20,6 ± 4,3

11,7±17,6 (RDI)

19,6±23,5 (RDI)

PLMI SG

11,7 ± 3,4

41,1±62,3

PLMI CG

1,9 ± 0,7

20,1±23,2

19,7±33,3

MSLT SG

5,9±4,9

MSLT CG

11,5±6,0

12,1±6,7

* Data given as median and semi-interquartil interval

#Summarizing (from the abstract): ‘SWS may be associated with dysfunction of the cerebral cortex in stroke patients as well as in normal aged subjects’

SG = Stroke Group; CG = Control Group