Table 1.

Description of the D1 (Original DBs) Databases in Terms of Provenance and Data Items Collected from Each Data Source

PROVENANCE OF DATA SOURCE		COMBINATION OF DATA SOURCES AND DATA ITEMS AVAILABLE IN THE DBS OF THE NETWORK
		IN-MATRICE	IN EU-ADR							IN MINI-SENTINEL			IN OMOP
		MA1	EU1	EU2	EU3	EU4	EU5	EU6	EU7	MS1	MS2	MS3	O1	O2	O3	O4
Primary care	Administrative data									Dx Proc	Dx Proc	Dx Proc	Dx Proc	Dx Proc	Dx Proc
	Clinical data						Dx	Dx Rx Text Refspec Refinpat Vac	Dx Rx Text Refspec Refinpat Res	Dx Proc						Dx Rx
Secondary care	Administrative data	Spec Proc	Spec Proc	Spec Proc	Dx Proc					Dx Proc	Dx Proc	Dx Proc	Dx Proc	Dx Proc	Dx Proc
	Clinical data									Dx Proc					Dx Rx Text
Inpatient care	Administrative data	Dx Proc	Dx Proc	Dx Proc	Dx Proc	Dx Proc				Dx Proc	Dx Proc	Dx Proc	Dx Proc	Dx Proc	Dx Proc
	Clinical data									Dx Proc
Enrollment into the data collection		Geo	Geo	Geo	Geo	Geo	Charge	Charge	Charge	Elig	Elig	Elig	Elig	Elig	Elig	Elig
Pharmacies		Rx	Rx	Rx	Rx	Rx				Rx	Rx	Rx	Rx	Rx	Rx
Registry of disease-specific exemptions from copayment of healthcare		Dx	Dx	Dx
Death registry				Dx	Dx					Dx	Dx	Dx
Vaccination registry										Vac	Vac
Laboratory		Lab	Lab	Lab	Res	Res		Res		Res	Res			Res

Notes: If more than one database in a network has access to the same combination of data, they are represented by a single column. Data items—Dx: diagnostic codes; Proc: procedure codes; Rx: prescriptions or dispensings of drugs; Spec: specialty of secondary care encounters; Refsec: Referrals from secondary care; Refinpat: Referrals from inpatient care; Text Notes in free text; Lab: Labels of laboratory tests; Res: Laboratory test results; Vac: Vaccines; Geo: Presence in a geographical area; Charge: Being in assisted by a GP; Elig: Satisfying eligibility criteria for an insurance company or health plan.