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. 2016 Mar 7;11(3):e0150310. doi: 10.1371/journal.pone.0150310

Table 6. Oncologic safety of EABS as reported in the literature and in the current study.

Author year Journal Number OP method margin positive Follow-up(m) Local recurrence Distant metastasis Death
Tamoki21 2001 Surg Laparosc Endosc Percutan Tech 6 E-PM 0% one margin+ & convert TM
Lee22 2006 World J Surg 20 E-PM 10%(2/20) Cosmetic f/u 3m
Yamashita19 2006 J Nippon Med Sch 82 E-PM 0% 25 0% 0%
Yamashita38 2008 Am J Surg 20 E-PM 0% 12 0% 0%
Nakajima24 2009 Ann Surg 551 E-PM 20.5%(113/551) 35 4.2%(23/551) 4.5%(25/551) 1.3%(7/551)
Park27 2011 J Breast Cancer 40 E-PM 5%(2/40) 12 0%
681 BCS 10.6%(85/681) 12 0.3%(2/681)
Ozaki28 2013 J Laparoendosc Adv Surg Tech 73 E-PM 1.4%(1/73) 18.1(12–30) 0%
90 BCS 43.7(14–70) 1.1%(1/90)
Takahashi29 2014 Surg Today 100 E-PM 4% 23(9–40) 0% 0% 0%
150 BCS 3.3% 0% 0% 0%
T-EBSCG 2016 Current study 46 E-PM 6.5%(3/46) 26.8 (3.3–68.6) 0% 0% 0%
Author year Journal Number OP method Reconstruction Margin positive Nipple ischemia Follow-up(m) Local recurrence Death Prothesis loss
Nakajima34 2002 Biomed Pharmacother 17 E-NSM LDMF 0(0%) 14
Ho32 2002 Surg Endosc 9 E-NSM prothesis, average 235 ml 0(0%)
Ito37 2008 ANZ J Surg 33 E-NSM Prothesis, 30/33 (90.9%) average 235 ml 8(24.3%) and excised NAC 3(9.1%) necrosis 51.2 (16–86) 0 9.1%(3/33) infection with prosthesis removed
Fan30 2009 Chinese Med J 43 E-NSM implant 0(0%) 11.6% (5/43) 16.9±11.2 (6–48) 0 0
Sakamoto23 2009 Ann Surg Oncol 87/89 E-NSM no mention 0%, nipple involved 2(2.2%) 18%(16/89) 52 (16–80) 0
Tukenmez33 2014 J Laparoendosc Adv Surg Tech 10/11 E-NSM prothesis, implant 4, expander 6 0%,subnipple biopsy 1 (9.1%) positive 0% 3
T-EBSCG 2016 Current study 269 E-NSME-SSM Prothesis: implant, expander, TRAM 3/269 (1.1%) 12.5% (25/199) 26.8 (3.3–68.6) 1.1 (3/269%) 0.4% (1/269) Prothesis loss: 2.1%(3/143)

m: months, TM: total mastectomy, f/u: follow-up, E-PM: endoscopic assisted partial mastectomy, E-NSM: endoscopic assisted nipple sparing mastectomy, E-SSM: endoscopic assisted skin sparing mastectomy, BCS: breast conserving surgery, LDMF: latissimus dorsi myocutaneous flap, TRAM: transverse rectus musculocutaneous flap.