Table 1. Causes of death among multi-drug resistant tuberculosis patients who died during treatment or follow-up, North West Province, South Africa, 2000–2008, N = 199.
| Cause of death and treatment stage | HIV Infection Status | Total | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| HIV-infected and access to ART | HIV-negative | |||||||||
| ART during treatment | No ART | Total | ||||||||
| n | % | n | % | n | % | n | % | n | % | |
| Death during treatment | ||||||||||
| TB | 27 | 79.4 | 50 | 56.2 | 773 | 62.6 | 243 | 68.6 | 1013 | 63.9 |
| AIDS1 | 7 | 20.6 | 38 | 42.7 | 45 | 36.6 | 0 | - | 454 | 28.5 |
| Other2 | 0 | - | 1 | 1.1 | 1 | 0.8 | 11 | 31.4 | 125 | 7.6 |
| Total | 34 | 100.0 | 89 | 100.0 | 123 | 100.0 | 35 | 100.0 | 1586 | 100.0 |
| Death post treatment | ||||||||||
| TB | 1 | 50.0 | 11 | 39.3 | 12 | 40.0 | 5 | 45.5 | 17 | 41.5 |
| 0 | - | 17 | 41.5 | |||||||
| 6 | 54.5 | 7 | 17.1 | |||||||
| AIDS1 | 1 | 50.0 | 16 | 57.1 | 17 | 56.7 | ||||
| Other2 | 0 | - | 1 | 3.6 | 1 | 3.3 | ||||
| Total | 2 | 100.0 | 28 | 100.0 | 30 | 100.0 | 11 | 100.0 | 41 | 100.0 |
| Overall Total | 36 | 117 | 153 | 46 | 199 | |||||
1 = AIDS-related sequelae: liver failure, cancer, Cryptococcus meningitis, lactic acidosis, Kaposi sarcoma, malaria, Pneumocystis pneumonia and a pulmonary embolus
2 = Other causes: liver disease, corpulmonale, diabetes, pneumonia, epilepsy, motor vehicle accident and suicide
3 = Cohort TB specific case fatality rate = 101/671 = 15.1%; Rate among HIV-negative = 24/278 = 8.6%; Rate among HIV-positive = 77/393 = 19.6%
4 = Cohort Rate of mortality due to other causes = 12/671 = 1.8%
5 = Cohort Surplus deaths due to HIV-infected patients = 45/671 = 6.7%
6 = Cohort Death rate = 158/671 = 23.5%