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Two mTOR complexes and their functions. mTORC1 is composed of mTOR, mLST8, raptor and PRAS40. Its function is involved many growth-related processes and oxygen adaptation and is sensitive to rapamycin. mTORC2 shares mTOR and mLST8 with mTORC1, but contains a few other unique components, including rictor, mSIN1 and PRR5
