Table 5.
Comparison of the first model generated by different pipelines.
Pipeline | TM-scorea | GDT-TSa | GDT-HAa | TMtemplateb |
---|---|---|---|---|
LOMETS | 0.613 | 0.532 | 0.387 | |
QUARK-TBM | 0.634 | 0.546 | 0.393 | 0.798 (0.644) |
I-TASSERc | 0.642 (0.011) | 0.553 (0.016) | 0.394 (0.396) | 0.763 (0.637) |
I-TASSER+QUARKd | 0.650 (0.022) | 0.561 (0.021) | 0.401 (0.041) | 0.773 (0.639) |
TM-, GDT-TS and GDT-HA scores of the first models compared to the native. The values in parenthesis are the p-value compared to the models generated by the previous row (i.e., p-value of I-TASSER vs.QUARK -TBM, and I-TASSER-QUARK vs. I-TASSER).
TM-score of the first model to the closest template. The value in parenthesis is the average TM-score of the first model to the top 30 closest templates.
I-TASSER without using QUARK-TBM models
I-TASSER predictions using QUARK-TBM models as input. These models were finally submitted to CASP.