Table 3. Multivariable Analysis for ORs with 95% CIs of Thyroid Cancer According to Clinical Characteristics.
Adjusted OR | P | Adjusted OR* | P | Adjusted OR† | P | |
---|---|---|---|---|---|---|
Age < 20 or > 60 | 0.694 (0.522, 0.923) | 0.012 | 0.698 (0.524, 0.928) | 0.013 | 0.695 (0.523, 0.924) | 0.012 |
Male gender | 1.394 (1.071, 1.814) | 0.013 | 1.382 (1.062, 1.797) | 0.016 | 1.365 (1.050, 1.774) | 0.020 |
1st degree family history | 1.618 (1.088, 2.405) | 0.018 | 1.612 (1.084, 2.397) | 0.018 | 1.655 (1.114, 2.458) | 0.013 |
Solitary lesion on US | 1.182 (0.933, 1.498) | 0.167 | 1.180 (0.931, 1.495) | 0.172 | 1.193 (0.942, 1.512) | 0.143 |
Serum TSH level | 1.171 (1.033, 1.327) | 0.013 | ||||
TSH grade | 0.029 | |||||
0.3–1.39 | 1 | |||||
1.4–2.49 | 1.317 (1.031, 1.681) | 0.027 | ||||
2.5–4.99 | 1.415 (1.029, 1.947) | 0.033 | ||||
TSH grade | ||||||
0.3–2.49 | 1 | |||||
2.5–4.99 | 1.258 (0.931, 1.699) | 0.135 | ||||
C-statistics | 0.591 (0.560, 0.622) | 0.586 (0.555, 0.616) | 0.580 (0.550, 0.610) |
Numbers in parentheses are 95% CIs. *TSH levels were categorized into three groups: relatively low in normal range, mid-normal, relatively high in normal range, †TSH levels were categorized into two groups: low and mid normal, relatively high in normal range. 1st degree = first-degree, CIs = confidence intervals, OR = odds ratio, TSH = thyroid stimulating hormone, US = ultrasonography