Table 4. Multivariable Analysis for ORs with 95% CIs of Thyroid Cancer According to Clinical and US Characteristics.
Adjusted OR | P | Adjusted OR* | P | Adjusted OR† | P | |
---|---|---|---|---|---|---|
Age < 20 or > 60 | 0.812 (0.550, 1.199) | 0.295 | 0.810 (0.548, 1.196) | 0.288 | 0.810 (0.548, 1.195) | 0.288 |
Male gender | 1.994 (1.360, 2.925) | < 0.001 | 1.996 (1.362, 2.925) | < 0.001 | 1.994 (1.361, 2.921) | < 0.001 |
1st degree family history | 1.278 (0.742, 2.203) | 0.377 | 1.281 (0.743, 2.209) | 0.373 | 1.283 (0.744, 2.211) | 0.370 |
Solitary lesion on US | 1.413 (1.014, 1.970) | 0.041 | 1.409 (1.011, 1.965) | 0.043 | 1.410 (1.012, 1.966) | 0.043 |
Serum TSH level | 1.046 (0.881, 1.242) | 0.605 | ||||
TSH grade | 0.757 | |||||
0.3–1.39 | 1 | |||||
1.4–2.49 | 1.020 (0.729, 1.427) | 0.907 | ||||
2.5–4.99 | 1.176 (0.762, 1.816) | 0.464 | ||||
TSH grade | ||||||
0.3–2.49 | 1 | |||||
2.5–4.99 | 1.166 (0.776, 1.752) | 0.461 | ||||
US assessment | 39.778 (27.953, 56.606) | < 0.001 | 39.870 (28.003, 56.765) | < 0.001 | 39.927 (28.065, 56.802) | < 0.001 |
C-statistics | 0.874 (0.855, 0.894) | 0.874 (0.855, 0.894) | 0.874 (0.855, 0.894) |
Numbers in parentheses are 95% CIs. *TSH levels were categorized into three groups: relatively low in normal range, mid-normal, relatively high in normal range, †TSH levels were categorized into two groups: low and mid normal, relatively high in normal range. 1st degree = first-degree, CIs = confidence intervals, OR = odds ratio, TSH = thyroid stimulating hormone, US = ultrasonography