Table 1.
Clinical characteristics of patients receiving ECMO reported to the ACMT ToxIC Registry. Three patients were seen at facilities that did not participate in our study
| Age (gender) | Exposure | Signs/symptoms | Other interventions | Reason for ECMO | Time to ECMO from presentation | Duration of ECMO | Survival |
|---|---|---|---|---|---|---|---|
| 7 months (F) | Carbon monoxide, smoke inhalation | Coma Metabolic acidosis |
Dopamine | Poor ventilation | <1 day | 12 days | Y |
| <2 years (M) | Metformin | Ventricular dysrhythmias Coma Agitation Metabolic acidosis |
CRRT | NA | NA | NA | Y |
| 2 years (F) | Flecainide | Hypotension Bradycardia Ventricular dysrhythmias Wide QRS Seizures |
Fat emulsion Sodium bicarbonate CPR |
Cardiovascular arrest, cardiac dysrhythmia | 4 h | 4 days | Y |
| 4 years (M) | Carbon monoxide, smoke inhalation | Coma Metabolic acidosis Rhabdomyolysis |
Hydroxocobalamin | Poor ventilation | 1 day | 8 days | Y |
| 17 years (F) | Methanol | Metabolic acidosis Hypotension Tachycardia Seizure |
Vasopressors CRRT Bicarbonate Fomepizole |
Persistent acidosis and persistent hypotension | 8 h | 15 h | N |
| 18 years (M) | Diphenhydramine Quetiapine |
Hypotension Bradycardia Ventricular dysrhythmias Prolonged QT interval ARDS Coma Seizures Metabolic acidosis |
Fat emulsion | NA | NA | NA | N |
| 22 years (F) | Bitter almond | Hypotension Tachycardia Ventricular dysrhythmias ARDS Coma Metabolic acidosis AKI Rhabdomyolysis |
Atropine Sodium bicarbonate Vasopressors CRRT CPR |
Cardiovascular arrest, ARDS | 4 days | 7 days | Y |
| 42 years (F) | Verapamil Citalopram |
Bradycardia ARDS Coma Metabolic acidosis AKI Rhabdomyolysis |
Vasopressors CRRT CPR |
Cardiovascular arrest, respiratory failure | 3 days | 9 days | Y |
| 48 years (M) | Metformin Trazodone Clonazepam |
Hypotension Bradycardia Ventricular dysrhythmias ARDS Coma Hypoglycemia Metabolic acidosis AKI Hemolysis |
Calcium Methylene blue Sodium bicarbonate Thiamine Albuterol Antiarrhythmics Anticonvulsants Glucose CRRT CPR |
Persistent acidosis, Poor ventilation | 17 h | 9 days | Y |
| 19–65 years (F) | Diphenhydramine Tramadol |
Hypertension Prolonged QTc Aspiration pneumonitis Hallucinations Metabolic acidosis AKI |
Cyproheptadine Deferoxamine Antiarrhythmics HD |
NA | NA | NA | Y |
NA information not available, local sites did not participate in data extraction, CRRT continuous renal replacement therapy, CPR cardiopulmonary resuscitation, HD hemodialysis, AKI acute kidney injury, ARDS acute respiratory distress syndrome