Skip to main content
. 2016 Feb 21;11:287–290. doi: 10.1016/j.nicl.2016.02.008

Table 1.

Volumetry of cerebellar subregions in 18 healthy non-carrier controls and 44 genetic FTD patients. Values denote mean and standard deviation (SD) volumes in mm3 or n (%). p-values denote significance on Mann–Whitney U test. Bold represents a significant difference between groups after correcting for multiple comparisons.

 Controls (18)
 C9orf72 (17)
 MAPT (20)
 GRN (7)
 C9orf72 vs Controls
 MAPT vs Controls
 GRN vs Controls
 C9orf72
 MAPT
 GRN
 GRN vs C9orf72
 GRN vs MAPT
 C9orf72 vs MAPT
Structure Mean SD Mean SD Mean SD Mean SD p-Value p-Value p-Value % difference vs controls % difference vs controls % difference vs controls p-Value p-Value p-Value
Lobule I–IV 6236 670 6363 861 6250 433 7053 674 0.660 0.534 0.012 − 2.0 − 0.2 − 13.1 0.099 0.013 0.775
Lobule V 8911 897 8623 905 8922 742 9371 737 0.503 0.553 0.125 3.2 − 0.1 − 5.2 0.034 0.145 0.311
Lobule VI 15639 1452 14587 2000 15277 1390 16590 1930 0.067 0.534 0.244 6.7 2.3 − 6.1 0.034 0.104 0.133
Lobule VIIa-Crus I 21091 2467 17885 1984 20360 3303 19298 2237 < 0.0005 0.675 0.125 15.2 3.5 8.5 0.099 0.498 0.013
Lobule VIIa-Crus II 17610 2311 15807 2863 16015 1822 17666 752 0.067 0.033 0.534 10.2 9.1 − 0.3 0.147 0.036 0.845
Lobule VIIb 7565 802 7330 976 7488 781 7460 611 0.483 0.515 0.534 3.1 1.0 1.4 0.951 0.850 0.729
Lobule VIIIa 7799 704 7724 927 7957 558 8033 756 0.909 0.361 0.495 1.0 − 2.0 − 3.0 0.534 0.766 0.517
Lobule VIIIb 7451 900 6926 894 7318 1077 7233 834 0.245 0.806 0.790 7.0 1.8 2.9 0.288 0.685 0.270
Lobule IX 6200 828 5563 799 5520 709 5659 864 0.013 0.010 0.158 10.3 11.0 8.7 0.318 0.533 0.988
Lobule X 860 88 850 108 909 124 882 146 0.883 0.228 1.000 1.1 − 5.7 − 2.6 0.757 0.607 0.149
Vermis 5034 375 4624 584 4554 412 4862 408 0.025 0.001 0.297 8.1 9.5 3.4 0.260 0.145 0.940
Dentate nuclei 3291 426 3303 406 3214 422 3325 524 1.000 0.361 0.836 − 0.4 2.3 − 1.0 0.951 0.766 0.341
Interposed nuclei 392 44 351 31 357 31 394 54 0.004 0.007 0.836 10.4 8.9 − 0.4 0.099 0.104 0.821
Fastigial nuclei 57 10 51 6 51 6 56 10 0.062 0.033 0.836 10.5 11.1 0.9 0.147 0.104 0.988