Table 1.
Sample and subject characteristics (N = 1117) of participants with plasma 8-OHdG and/or F2-isoprostane measurement.
| Mean (SD) or % | |
|---|---|
| Sociodemographics | |
| Age (years) | 42.5 (14.1) |
| Female | 64.7% |
| Education (years) | 12.7 (3.2) |
| North-European ancestry | 96.6% |
|
| |
| Lifestyle | |
| Smoking | |
| None (never/former) | 69.3% |
| <10 cig/day | 14.8% |
| ≥10 cig/day | 15.9% |
| Plasma cotinine ng/mL | 71.2 (175.9) |
| Alcohol | |
| ♂/♀ < 1 units/wk | 23.2% |
| ♂ ≤ 21/♀ ≤ 14 units/wk | 65.0% |
| ♂ > 21/♀ > 14 units/wk | 11.8% |
| Physical activity (MET-min/wk) | 3742 (3072) |
| Body mass index (BMI) (kg/m2) | 25.3 (4.5) |
| Supplement users | 11.5% |
|
| |
| Metabolic, health, and disease factors | |
| Waist circumference (cm) | 88.5 (13.4) |
| Triglycerides (mmol/liter) | 1.3 (0.9) |
| HDL-cholesterol (mmol/liter) | 1.6 (0.4) |
| LDL-cholesterol (mmol/liter) | 3.1 (1.0) |
| Fasting glucose (mmol/liter) | 5.2 (0.9) |
| Systolic blood pressure (mmHg) | 137 (20) |
| Diastolic blood pressure (mmHg) | 81 (11) |
| Metabolic syndrome (MetS) | 19.6% |
| N of MetS components | 1.4 (1.3) |
| N chronic diseases | |
| 0 | 62.3% |
| 1 | 26.6% |
| 2 or more | 12.1% |
| Cardiometabolic (cardiovascular disease, diabetes) | 8.7% |
| Musculoskeletal (osteoarthritis, rheumatic disorders) | 9.4% |
| Chronic nonspecific lung disease | 6.5% |
| Cancer | 3.3% |
|
| |
| Sampling variables | |
| Season at time of sample collection | |
| Winter (Dec.–Feb.) | 20.3% |
| Spring (Mar.–May) | 24.5% |
| Summer (Jun.–Aug.) | 24.5% |
| Autumn (Sep.–Nov.) | 30.6% |
| Fasting prior to sample collection | 95.6% |
|
| |
| Oxidative stress markers | |
| 8-Hydroxy-2′-deoxyguanosine (8-OHdG) (pmol/liter) | 45.5 (17.0) |
| F2-isoprostanes (pmol/liter) | 120.6 (40.4) |
Cig: cigarettes; HDL: high-density lipoprotein; LDL: low-density lipoprotein; N: number; MET: metabolic equivalent of task; MetS: metabolic syndrome; Wk: week.