Table 4.

Statistic summary of forest plot of comparison: 5-year overall survival of LSS vs. amputation for the treatment of osteosarcoma.

Study	LSS		Amputation		Weight (%)	Odds Ratio
	Events	Total	Events	Total		M–H, Fixed, 95% CI
Abudu et al.	17	27	6	13	4.0	1.98 [0.52, 7.58]
Bacci et al.b	60	95	230	465	38.5	1.75 [1.11, 2.76]
Guo et al.	9	13	3	8	1.5	3.75 [0.59, 23.94]
Hegyi et al.	58	92	23	30	17.2	0.52 [0.20, 1.34]
Jiang et al.	25	32	19	32	5.6	2.44 [0.82, 7.31]
Ma et al.	12	32	7	19	7.4	1.03 [0.32, 3.33]
Niu et al.	8	12	4	10	1.9	3.00 [0.52, 17.16]
Scully et al.	19	30	12	22	6.8	1.44 [0.47, 4.41]
Xu et al.	19	43	8	15	8.9	0.69 [0.21, 2.25]
Zhang et al.	6	17	1	14	1.0	7.09 [0.74, 68.24]
Zhao et al.	19	37	8	16	7.3	1.06 [0.33, 3.41]
Total (95%) CI	252	430	321	644	100.0	1.47 [ 1.10, 1.97]

Heterogeneity: χ²=11.94, df=10 (P=0.29); I²=16%.

Test for overall effect: Z=2.61 (P=0.009).