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. 2016 Mar 1;30(5):522–534. doi: 10.1101/gad.271890.115

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© 2016 Yan et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 1. — PCBP4-deficient mice are prone to lung cancer and lymphoma. (A) Kaplan-Meier survival curve for wild-type (WT) (median survival time 110.4 wk ± 1.1 wk), PCBP4^+/− (median survival time 102.1 wk ± 3.2 wk), and PCBP4^−/− (median survival time 105.3 wk ± 9.8 wk) mice. (B) PCBP4^+/− and PCBP4^−/− mice are prone to lung cancer and lymphoma. (*) P < 0.05. (C) Representative images of H&E-stained normal lungs in wild-type mice and lung adenocarcinomas (ADCs) in PCBP4^+/− and PCBP4^−/− mice.