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. 2016 Mar 3;7:10827. doi: 10.1038/ncomms10827

Figure 2. Distinguishing features of the envoplakin PRD structure.

Figure 2

(a) Ribbon representation of the envoplakin PRD. Plakin repeats 1–5 are coloured red, green, blue, yellow and purple, respectively, with their PR motifs and secondary structural elements labelled. The N and C termini are labelled and shown in teal. The arrow indicates the kink of H2 in PR2. (b) Overlay of PR3 from envoplakin (magenta) and desmoplakin PRDs B (olive) and C (grey). (c) Overlay of PR4 from envoplakin and desmoplakin PRDs B and C. (d) Stabilization of the envoplakin PR3 by hydrogen bonding (black-dashed lines). (e) Stabilization of PR4 by hydrogen bonding.