Table 4.

Less commonly used antihypertensive plants with antiproliferative activity.

Herb	Effect/Mechanism	Concentration/Dose	Model	References
Angelica sinensis and Ligusticum chuanxiong	Arrests VSMCs at G0/G1	300 μg/ml	Rat vascular smooth muscles	Hou et al., 2005
Raphanus sativus	Arrests VSMCs in G1 phase	20–160 μg/ml	Mouse aortic smooth muscle cells	Suh et al., 2006
Sophora flavescens Ait	Inhibits hypoxia or TGF-β-induced proliferation	0.5–0.2 mg/ml	Pulmonary arterial smooth muscle cells	Zhang et al., 2014
Tribulus terrestris	Inhibits Ang II-induced proliferation	0.240 mg/ml of the plant's total saponins	Primary VSMCs from aorta of newborn calves	Li et al., 2013