Table 5.

Less commonly used antihypertensive plants with diuretic activity.

Herb	Effect/Mechanism	Concentration/Dose	Model	References
Elettaria cardamomum	Increases urine output and enhances Na+ and K+ excretion	1, 3, and 10 mg/kg	Anesthetized rats	Gilani et al., 2008
Lepidium latfolium	Increases urine output and electrolyte excretion	50–100 mg/kg	Rats	Navarro et al., 1994
Lepidium sativum	Increases electrolyte excretion	20 mg/kg	SHR	Maghrani et al., 2005
Phyllanthus amarus	Increases urine volume and Na+ levels in serum (humans) and decreases SBP and DBP (in man)	80 mg/kg (in rabbits)	Mild hypertensive patients and rabbits	Srividya and Periwal, 1995; Amaechina and Omogbai, 2007
Tropaeolum majus L	Reduces aldosterone	300 mg/kg ethanolic extract, 200 mg/kg purified fraction, 10 mg/kg isoquercitrin	SHR	Gasparotto Junior et al., 2012
	Downregulates renal Na+/K+ pump
	Increases urine volume
Viscum articulatum Burm	Increases urine volume	200 mg/kg/day	L-NAME-treated rats	Bachhav et al., 2012
	Increases urine volume, electrolyte excretion and glomerular filtration rate	100, 200, and 400 mg/kg	Male Wistar rats	Jadhav et al., 2010