. Author manuscript; available in PMC: 2016 Mar 8.

Published in final edited form as: Br J Haematol. 2015 Sep 7;171(4):638–646. doi: 10.1111/bjh.13641

Table II.

Coagulation data in study subjects.

Analyte	AA (n = 22)		SS (n = 16)	P-value^*	P-value^†
D-Dimer (μg/ml)
<150	14 (64%)	3 (18%)	0 (0%)	0.0171	<0.0001
150–229	3 (14%)	4 (24%)	0 (0%)
>229	5 (23%)	10 (29%)	16 (100%)
TAT (nmol/l)	0.02 (0.02–0.02)	0.03 (0.02–0.97)	3.04 (0.03–8.78)	0.0385	<0.0001
Whole blood tissue factor activity (pmol/l)	0.08 (0.04–0.14)	0.09 (0.04–0.11)	0.23 (0.09–0.33)	0.7337	0.0048
Microparticle tissue factor activity (fmol/l)	2.2 (0–3.5)	3.8 (2.8–6.9)	5.5 (4.5–9.3)	0.0513	0.0042

Data are presented as median (IQR) or n (%).

AA, HbAA individuals (controls); AS, HbAS individuals (sickle cell trait); SS, HbSS individuals (sickle cell disease); TAT, thrombin-antithrombin complex.

Comparison of AA to AS.

^†

Comparison of AA to SS.