Table 5. Number of immune responders in sequential and concurrent chemoimmunotherapy split by apoptosis.
|
Sequential chemoimmunotherapy arm |
Concurrent chemoimmunotherapy arm |
||||
|---|---|---|---|---|---|
|
Immune responsea |
Immune responsea |
||||
| Apoptosisb | Yes (n=5) | No (n=5) | Apoptosisb | Yes (n=9) | No (n=11) |
| Yes (n=2) | 1 | 1 | Yes (n=5) | 2 | 3 |
| No (n=8) | 4 | 4 | No (n=15) | 7 | 8 |
| Apoptosisc | Yes (n=5) | No (n=5) | Apoptosisc | Yes (n=9) | No (n=11) |
| Yes (n=5) | 2 | 3 | Yes (n=14) | 6 | 8 |
| No (n=5) | 3 | 2 | No (n=6) | 3 | 3 |
| Two-tailed Fisher's exact test | P=1.00 | P=1.00 | |||
a
Defined as T-cell proliferative response or positive delayed-type hypersensitivity (DTH).
b
Defined as ⩾30% increase in M30 value at 48 h.
c
Defined as ⩾10% increase in M30 value at 48 h.