Table 1.
Prognostic factors in cases of threatened abortion
| Favourable prognostic factors | Adverse prognostic factors |
|---|---|
| History | |
| Advancing gestational age1* | Maternal age >34 years4w3*w4* |
| Increasing number of previous miscarriagesw4* | |
| Sonography | |
| Fetal heart activity at presentation6-8 | Fetal bradycardia1* |
| Discrepancy between gestational age and crown to rump length4,12 | |
| Empty gestational sac >15-17 mm5,6 | |
| Maternal serum biochemistry | |
| Normal levels of these markers | Low β hCG values10 |
| Free β hCG value of 20 ng/ml11 | |
| β hCG increase <66% in 48 hrsw9* | |
| Bioactive/immunoreactive ratio hCG <0.5w7 | |
| Progesterone <45 nmol/l in 1st trimester17 | |
| Inhibin A <0.553 multiples of median18 | |
| CA125 level ≥43.1 U/mL in 1st trimester19 |
*
Women without symptoms of threatened abortion.