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. 2004 Jul 17;329(7458):152–155. doi: 10.1136/bmj.329.7458.152

Table 2.

Pregnancy outcome in studies with various therapeutic regimens

Successful continuation of pregnancy
First author Design N Sonography at presentation Intervention Intervention group Controls P value
Mollerw11 Randomised controlled trial 260 No Medroxyprogesterone (three regimens) 60/123 71/137 0.62
Tognoniw12 Randomised controlled trial 145 No Hydroxyprogesterone caproate 49/74 50/71 0.58
Berlew13 Randomised controlled trial 300 No Hydroxyprogesterone caproate 96/154 100/146 0.26
Gerhardw14 Randomised controlled trial 52 Yes Progesterone 23/26 21/26 0.44
Soltanw16 Randomised controlled trial 35 Yes Buphenine 19/23 4/12 <0.01
Harrison22 Randomised controlled trial 61 Yes hCG 14/20 11/21 0.24
Harrison22 Randomised controlled trial 61 Yes Bed rest 5/20 11/21 0.07
Giobbe23 Retrospective 226 Yes Bed rest 123/146 64/80 0.41
Ben-Haroush24 Prospective observational 230 Yes Bed rest 180/200 23/30 0.03