Table 1.
Survival of An. gambiae and Cx. quinquefasciatus larvae at different ivermectin concentrations and exposure times
| Ivermectin concentrationb | Mean no. ± SD (range) surviving at 24 hoursa | Mean no. ± SD (range) surviving at 48 hoursa | ||||
|---|---|---|---|---|---|---|
| An. gambiae | Cx. quinquefasciatus | p-value* | An. gambiae | Cx. quinquefasciatus | p-value* | |
| 0.0 | 25.0 ± 0.0 (25–25) | 25.0 ± 0.0 (25–25) | NS | 24.9 ± 0.3 (24–25) | 24.1 ± 1.3 (21–25) | NS |
| 0.001 | 24.9 ± 0.3 (24–25) | 22.3 ± 2.5 (17–25) | 0.002 | 23.7 ± 1.3 (21–25) | 19.3 ± 4.4 (12–25) | 0.003 |
| 0.01 | 24.8 ± 0.5 (24–25) | 11.8 ± 5.3 (4–22) | <0.001 | 20.2 ± 2.5 (15–23) | 4.5 ± 3.9 (0–12) | <0.001 |
| 0.1 | 15.4 ± 6.3 (3–23) | 0.0 (0–0) | - | 0.08 ± 0.3 (0–1) | 0.0 (0–0) | - |
| 1.0 | 0.0 (0–0) | 0.0 (0–0) | - | 0.0 (0–0) | 0.0 (0–0) | - |
| 10.0 | 0.0 (0–0) | 0.0 (0–0) | - | 0.0 (0–0) | 0.0 (0–0) | - |
aTwelve replicates each with 25 larvae
bIn parts per million
*t-test