Table 3.
The influence of NTG on arrhythmias in NTG-tolerant rats with acute myocardial infarction
| Group of animals | Monitoring started after 1 h of AMI and lasted during 1 h | |||||
|---|---|---|---|---|---|---|
| VT | VPBs | VF | ||||
| Number of animals having VT | Average duration in seconds in each animal | Number of animals having VPBs | Average number of VPBs in each animal | Number of animals having VF | Average duration in seconds in each animal | |
| Control, n = 18 | 6 | 9 ± 2 | 12 | 440 ± 30 | – | – |
| I—NTG, n = 20 | 11 | 19 ± 4** | 7 | 520 ± 24* | 2 | 66 ± 12 |
| II—NTG + CGRP antagonist, n = 20 | 13 | 24 ± 6** | 4 | 668 ± 52**# | 3 | 85 ± 14# |
VT ventricular tachycardia, VPBs ventricular premature beats, VF ventricular fibrillation, n number of animals in each group
Difference with the control group: *p < 0.05; **p < 0.01; difference with the I—NTG-tolerant group: # p < 0.05