Table 1.

Percentages of patients not respond to initial dose with different opioid administration

78 female patients
	Fentanyl	Morphine	Oxycodone
Low chol	5 (15)	1 (2)	5 (11)
Medium chol	0 (13)	0 (4)	2 (8)
High chol	0 (13)	0 (7)	0 (5)
Sum	5 (41)	1 (13)	7 (24)
204 male patients
Low chol	11 (32)	2 (10)	18 (29)
Medium chol	0 (27)	1 (4)	10 (28)
High chol	1 (35)**	1 (8)	6 (31)*
Sum	20 (94)	4 (22)	34 (78)

Patients were classified into three groups, low, medium and high cholesterol groups, depending on their serum total cholesterol levels. Patients in each group were further divided into three sub-groups depending which opioid they were administrated. The numbers of overall patients and patients who did not respond to initial doses and required higher doses of opioids were provided. Fisher’s exact test was used to do statistical analysis between low cholesterol group with other two groups