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. 2016 Mar 6;20:51. doi: 10.1186/s13054-016-1238-0

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© Hilbert et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Changes in angiopoietin and TIE2 serum levels upon coronary artery bypass graft (CABG). Serum was sampled from patients being scheduled for elective on-pump CABG before surgery (preop) and 1, 6 and 24 h after closure of the aortic clamp. Serum was analyzed for angiopoietin 1 (ANG1) (a), ANG2 (b) and soluble TIE2 receptor (sTIE2) (d) by enzyme-linked immunosorbent assay. Furthermore, the ANG2/ANG1 ratio was calculated (c). N = 28 (24-h time point, n = 26), median with percentile 25–75, *p <0.05, **p <0.01, ***p <0.001 (vs. preop). CPB cardiopulmonary bypass