Table 2.
Influence of the 24-h ANG2/ANG1 ratio
| Variable | ANG2/ANG1 | ANG2/ANG1 | p value |
|---|---|---|---|
| <0.18 | >0.18 | ||
| Details of patients and procedure | |||
| Preoperative ejection fraction, % | 60 (53–67) | 50 (44–55) | 0.01 |
| CPB time, minutes | 113 (90–125) | 110 (103–125) | 0.49 |
| Aortic cross-clamp/reperfusion time, minutes | 105 (85–120) | 105 (93–115) | 0.9 |
| Postoperative details (T24) | |||
| PaO2/FiO2 ratio | 407 (360–502) | 429 (182–481) | 0.79 |
| Lactate, mmol/l | 1.27 (1–1.4) | 1.32 (1.1–1.2) | 0.68 |
| Hgb, mmol/l | 9.7 (9.3–10.4) | 10.2 (9.1–11.6) | 0.52 |
| Crystalloid fluid balance, ml | 3100 (2340–3735) | 4830 (3310–5720) | 0.01 |
| Serum creatinine, mg/dl | 1.03 (0.9–1.12) | 0.98 (0.74–1.19) | 0.58 |
| Duration of mechanical ventilation, h | 16.5 (10.3–18.9) | 18.8 (17.1–20.2) | 0.12 |
| ICU LOS, h | 22.2 (21–35.4) | 44.4 (21.3–74.6) | 0.2 |
| LOS hospital, days | 14 (9–15) | 14 (11–21) | 0.12 |
The study population was divided into two groups according to the angiopoietin (ANG)2/ANG1 ratio measured 24 h after aortic de-clamping using the overall median ratio (0.18) as threshold value. Details are presented for patients, procedures, and postoperative variables recorded 24 h after admission to ICU (T 24). Median with percentile 25–75, two-tailed Mann–Whitney test. CPB cardiopulmonary bypass, PaO 2 arterial oxygen partial pressure, FiO 2 inspiratory oxygen fraction, Hgb hemoglobin, ICU LOS length of stay on intensive care unit, LOS hospital length of stay in hospital