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. 2016 Mar 8;16:6. doi: 10.1186/s12878-016-0045-9

Table 4.

Coagulation disorders in 24 cases (6 men [on testosterone] and 18 women [on estrogen]) who had testosterone/hormone therapy before PE, compared to 116 cases with PE but no hormone, no cancer (62 men, 54 women), and compared to 17 cancer cases (9 men, 8 women)

Factor V PTG MTHFR PAIG Homocys-teinea Lupus anticoagulant ACLA IgG ACLA IgM
Abnormal range TC,TT TC,TT TT 4G4G umol/l Positive Datedb Datedc
Hormone Cases (n = 24,
6 men on TT,
18 women on ET)
4/24
(17 %)
2/24
(8 %)
1/24
(4 %)
1/24
(4 %)
3/24
(13 %)
2/24
(8 %)
2/24
(8 %)
2/24
(8 %)
PE_no hormone, no Cancer (n = 116, 62 men, 54 women) 15/105
(14 %)
7/71
(10 %)
18/43
(42 %) **
17/68
(25 %)
1/61
(2 %)
5/58
(9 %)
Cancer (n = 17,
9 men, 8 women)
0/15
(0 %)
6/15
(40 %)
1/17
(6 %)
0/15
(0 %)
1/17
(6 %)

**p < .025, comparing with Hormone cases by Fisher’s test

adated cut point for Homocysteine high: ≥ 15 (11/15/08-12/2/14); ≥10.4 (after 12/3/14)

bdated cut point for IgG high: ≥ 23 GPL (before 10/31/12); ≥ 15 (after 11/1/12)

cdated cut point for IgM high: ≥ 10 MPL (before 4/30/12); ≥ 13 (after 5/1/12)