Table 3.

Multivariate cox proportional hazard model analyses of prognostic factors for ES-SCLC patients treated with chemotherapy

Factors	HR	95 % CI	p
Age ≥75	1.26	0.74–2.14	0.40
Female	2.38	1.11–5.12	0.027
PS 2–4	1.53	0.83–2.81	0.17
Tumor size >3 cm	2.44	1.05–5.68	0.038
Number of metastases ≥2	1.81	1.08–3.04	0.026
LDH high	1.88	0.96–3.67	0.064
Na low	2.50	1.31–4.78	0.006

Note: ES-SCLC extensive-stage small cell lung cancer, HR hazard ratio, CI confidential interval,P S performance status