Table 5.
Top 10 transcripts in both directions for the RIF1 analysis. The RIF1 analysis was performed on blood RNA DE genes contrasting AB minus AA animals.. The transcript ID, gene symbol and gene name is shown, together with the RIF1 calculated z-score. The positive RIF1 scores are > 2, which indicates a large difference between WUR genotypes in linkages to these hub genes
| Transcript_id | Gene symbol | Gene | RIF1 z-score |
|---|---|---|---|
| ENSSSCT00000001129 | TFAP2A | transcription factor AP-2 alpha | -0.863 |
| ENSSSCT00000000409 | MYL6 | myosin, light chain 6 | -0.862 |
| ENSSSCT00000000824 | LRTM2 | leucine-rich repeats and transmembrane domains 2 | -0.862 |
| ENSSSCT00000002712 | CATSPERB | catsper channel auxiliary subunit beta | -0.861 |
| ENSSSCT00000000267 | KRT5 | keratin 5 | -0.861 |
| ENSSSCT00000000210 | C1QL4 | complement component 1, q subcomponent-like 4 | -0.861 |
| ENSSSCT00000002491 | C15ORF55 | a.k.a. NUT midline carcinoma, family member 1 | -0.860 |
| ENSSSCT00000004145 | MOCOS | molybdenum cofactor sulfurase | -0.860 |
| ENSSSCT00000000450 | GPR182 | G protein-coupled receptor 182 | -0.860 |
| ENSSSCT00000000014 | - | Structural maintenance of chromosomes protein | -0.859 |
| ENSSSCT00000002033 | IQGAP1 | IQ motif containing GTPase activating protein 1 | 7.348 |
| ENSSSCT00000029413 | - | uncharacterized | 7.389 |
| ENSSSCT00000012040 | B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 7.530 |
| ENSSSCT00000012873 | ACTL6A | actin-like 6A | 7.691 |
| ENSSSCT00000011122 | TOMM20 | translocase of outer mitochondrial membrane 20 homolog | 8.054 |
| ENSSSCT00000001714 | PPARD | peroxisome proliferator-activated receptor delta | 8.557 |
| ENSSSCT00000006566 | ATAD2 | ATPase family, AAA domain containing 2 | 9.040 |
| ENSSSCT00000030357 | WDR5B | WD repeat domain 5B | 9.160 |
| ENSSSCT00000005554 | PSMC6 | proteasome 26S subunit, ATPase, 6 | 9.500 |
| ENSSSCT00000019067 | NPEPPS | aminopeptidase puromycin sensitive | 14.674 |