Table 2.
Region of MHC-DRB | Total AA | Variable AA [%] | dAA ± S.E. | dN ± S.E. | dS ± S.E. | Z [p] |
---|---|---|---|---|---|---|
All sites | 57 | 21 [36.8 %] | 8.857 ± 2.65 | 0.090 ± 0.03 | 0.018 ± 0.02 | 3.985 [0.000*] |
non-ABS sites | 42 | 10 [23.8 %] | 4.142 ± 1.88 | 0.051 ± 0.02 | 0.001 ± 0.00 | 2.745 [0.003*] |
ABS sites | 15 | 11 [73.3 %] | 4.715 ± 1.66 | 0.217 ± 0.10 | 0.068 ± 0.07 | 2.767 [0.003*] |
Note. This table shows the total number of amino acid codons [AA] as well as the number and percentage of variable amino acid codons [Variable AA] in the MHC-DRB second exon, the average [± S.E.] pairwise AA differences [dAA] between alleles, the average [± S.E.] rates of nonsynonymous [dN] and synonymous [dS] substitutions per site, and the one-tailed test of positive selection [Z] with p-values [p]. All standard errors were obtained from 1000 bootstrap replicates [83]