Figure 6.

MTT cell viability assay toxicity results as a function of administered and deposited dose for all ENMs dispersed in RPMI+10% FBS at 24h. Fitted lines for most ENM had an R² of 0.9 or better; for N110 (R² =0.8), and CeO₂ and TiO2 (R² ~0.65). The delivered dose estimates were derived from the VCM-ISDD model calculations with effective density measurements (Hinderliter et al 2010; Cohen et al 2014) reported in table 3. Reproduced in parts with permission from Pal et al. ACS Nano, 2014, 8 (9), pp 9003–9015.