Table 2.
Survival outcomes for adult brainstem gliomas.
| Entire cohort, N = 143, median OS (months) | 32.1 |
|---|---|
| Median OS by WHO Grade and histology (months): | |
| Glioblastoma | 14.8* |
| Anaplastic astrocytoma | 21.1 |
| Diffuse astrocytoma | 77.1 |
| Glioma NOS | 96.2 |
| No biopsy | 40.0 |
| Median OS by imaging features (months): | |
| Enhancing | 15.3** |
| Non-enhancing | 61.5 |
| Median OS by age (months): | |
| 18–21 years*** | 25.9# |
| 22–39 | 34.7 |
| 40–59 | 34.3 |
| 60 and over | 14.2 |
| Median OS by anatomic site (months): | |
| Midbrain | 66.0+ |
| Pons | 25.3 |
| Medulla | 51.3 |
p = 0.0104, log-rank test for trend, comparing OS for DA, AA, and GB.
p = 0.0007.
p = 0.2015 log-rank test for trend.
p = 0.20 log-rank test for trend comparing all ages.
p = 0.6434 log-rank test for trend comparing all sites, p = 0.0816, log-rank test, comparing pontine to other tumors sites.