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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Bioorg Med Chem. 2015 Feb 13;23(7):1507–1514. doi: 10.1016/j.bmc.2015.02.003

Figure 2.

Figure 2

Reducing gefitinib-induced cytotoxicity by curcumin derivatives. Non-transformed rat small intestinal cell line IEC-18 was treated with 40 μM gefitinib with 5 μM compound 1 (curcumin), 2 (dimethyl curcumin), 5, 10, or 23, for 24 h. Cytotoxicity was evaluated by MTT assay and expressed as proliferative index (%) standardized by untreated cells (100%). Effects of compounds were evaluated by student t-test and represented p<0.05 (*) or p<0.01 (**).