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. Author manuscript; available in PMC: 2016 Mar 8.
Published in final edited form as: Science. 2015 Aug 14;349(6249):742–747. doi: 10.1126/science.aaa8391

Fig. 1. Mus81 and Yen1 promote repair of broken replication forks.

Fig. 1

(A) Southern blot showing seDSBs formed on ChrVI after Flp-nickase induction. Approximate relative proportions of each DSB band are indicated below the location of the corresponding probe. (B) Serial 10-fold dilutions plated on YP-glucose and YP-galactose (Flp induction) to assay for repair defects in mutant strains. Arrows indicate the predominant direction of replication forks reaching the FRT.