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. 2016 Mar 8;7:47. doi: 10.3389/fphar.2016.00047

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Copyright © 2016 Crupi, Impellizzeri, Bruschetta, Cordaro, Paterniti, Siracusa, Cuzzocrea and Esposito.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of co-ultraPEALut on neurotrophin levels in spinal cord of mice subjected to SCI. Significant increases in BDNF, GDNF, NGF, NT-3 levels were observed in spinal cord of SCI mice treated with co-ultraPEALut treatment. β-actin was used as internal control. A representative blot of lysates obtained from each group is shown, and densitometric analysis of all animals is reported (N = 10 mice from each group; ^*p < 0.05 vs. sham group; ^#p < 0.05 vs. SCI group; ^##p < 0.01 vs. SCI group).