Generalized linear models were fit to estimate the association of tertiles of pre-dialysis calculated osmolality with the magnitude of intra-dialytic SBP decline (Tertile 1 was taken as the reference), after adjusting for age, gender (male versus female), race (black versus non-black), diabetes, ischemic heart disease, congestive heart failure, access type (fistula, graft, catheter), pre-dialysis SBP, UFR, serum calcium, albumin, and bicarbonate.