Table 2.
Baseline hemodialysis treatment blood pressure characteristics according to tertiles of pre-dialysis calculated osmolarity
| Total (N=3,142) | Calculated Osmolarity Tertile | Pa | |||
|---|---|---|---|---|---|
| 1 (n=1,048) | 2 (n=1,049) | 3 (n=1,045) | |||
| Pre-dialysis SBP (mmHg) | 150.4 ± 26.1 | 148.0 ± 26.9 | 150.7 ± 25.7 | 152.4 ± 25.6 | <0.001 |
| Minimum Intradialytic SBP (mmHg) | 110.0 ± 26.9 | 110.7 ± 27.6 | 109.2 ± 26.3 | 110.2 ± 26.8 | 0.4 |
| Postdialysis SBP (mmHg) | 135.5 ± 24.3 | 136.4 ± 24.8 | 135.0 ± 24.3 | 135.1 ± 24.0 | 0.3 |
| SBP decline (mmHg) | 40.5 ± 28.5 | 37.5 ± 29.2 | 41.7 ± 27.6 | 42.4 ± 28.6 | <0.001 |
| SBP variabilityb (mmHg) | 15.8 ± 8.4 | 15.5 ± 8.2 | 16.0 ± 8.4 | 15.9 ± 8.5 | 0.4 |
| UF volume (L) | 3.0 ± 1.2 | 3.0 ± 1.3 | 3.0 ± 1.2 | 3.1 ± 1.1 | 0.001 |
| UFR (ml/kg/h) | 12.8 ± 4.9 | 12.2 ± 5.2 | 12.8 ± 4.7 | 13.4 ± 4.8 | <0.001 |
| IDH | 1,733 (55.2) | 542 (51.7) | 598 (57.0) | 593 (56.8) | 0.02 |
Note: Values for categorical variables are given as number (percentage); values for continuous variables, as mean ± standard deviation.
Hemodialysis-associated blood pressure variables (± standard deviation) according to baseline dialysate sodium use (≤140 mmol/L vs. >140 mmol/L or modeling).
Abbreviations and definitions: SBP, systolic blood pressure; UF, ultrafiltration; UFR, ultrafiltration rate; IDH, intradialytic hypotension (defined as SBP decline >35 mmHg or nadir intra-dialytic SBP <90 mmHg).
P values refer to testing the null of no difference between groups, using analysis of variance for continuous variables and χ2 tests for categorical variables.
SBP variability was calculated as the standard deviation of all intra-dialytic SBP measurements.