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. Author manuscript; available in PMC: 2016 Mar 8.
Published in final edited form as: Annu Rev Neurosci. 2014;37:409–434. doi: 10.1146/annurev-neuro-062012-170320

Figure 2.

Figure 2

Meta-analytic connectivity modeling (MACM) with behavioral domain filtering. The images illustrate the regional and behavioral specificity of connections of the caudate nucleus. Connectivity was computed as coactivation frequency with a seed region (caudate nucleus), sampling across the entire BrainMap database. Activation likelihood estimation (ALE) was used to compute statistical significance of co-occurrences. Behavioral filtering used the top tier of the BrainMap behavioral domain hierarchy. The projection patterns closely matched those established in the primate literature and were confirmed by diffusion tensor imaging (DTI) tractography. Images are reproduced from Robinson and colleagues (2012), the original report of behaviorally filtered MACM connectivity mapping, with permission.