Figure 4.
Cell killing activity of VSVFH-αHER2. (a) 2 × 105 TE671 (left column) or SKOV3ip.1 (right column) cells were infected with VSVFH-αHER2#6-11 (αHER2#6-11) at a multiplicity of infection (MOI) of 1. At 3 days postinfection, cells were fixed with 5% glutaraldehyde and stained with 0.1% crystal violet. Representative pictures are shown. Bar = 200 µm. (b) 5 × 103 TE671 (left) or SKOV3ip.1 (right) cells per well of a 96-well plate were infected with the same viruses as described above with a MOI of 1 or 10. At 3 days postinfection, cell viability was measured and plotted, considering the cell viability of noninfected cells as 100%. Graphs show the average of three independent experiments plus SD.