Table 1. Quantification of oncolytic virus production in infected adherent ovarian cancer cells and spheroids.

	Adherent culturea
	HEYA8	SKOV3	OVCAR8
MYXV	1.38 ± 0.08 × 105	5.37 ± 0.21 × 105	1.30 ± 0.13 × 105
vvDD	7.78 ± 1.22 × 106	2.78 ± 0.35 × 106	2.83 ± 0.59 × 106
MRBV	5.52 ± 1.55 × 107	4.82 ± 1.11 × 107	2.38 ± 0.43 × 107
	Spheroid cultureb
	HEYA8	SKOV3	OVCAR8
MYXV	8.54 ± 2.07 × 105	1.75 ± 0.33 × 105	1.12 ± 0.34 × 105
vvDD	1.60 ± 0.21 × 106	3.12 ± 1.58 × 105	6.04 ± 1.39 × 105
MRBV	1.09 ± 0.15 × 108	6.80 ± 0.78 × 106	1.58 ± 0.41 × 106

^aIn adherent culture, 2.5 × 10⁴ cells were infected in 24-well dishes at MOI 10 (2.5 × 10⁵ pfu).

^bIn spheroid culture, 5 × 10⁴ cells were infected in 24-well Ultra-Low Attachment cluster plates at MOI 10 (5 × 10⁵ pfu).

MOI, multiplicity of infection.