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Widening in obese sedentary compared to lean sedentary animal (black arrows) due to: increase in inflammatory cells, plasmacystoid and lymphoid cells (red arrow); and infiltration of fat cells (yellow arrow). Exercise appears to protect the villi from widening. Obese exercise villi contain wider lumen (asterisk) and are devoid of fat cell infiltrate. Lean Sedentary (A), Obese Sedentary (B), Lean Exercise (C), Obese Exercise (D).
