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. 2016 Mar 8;11(3):e0150990. doi: 10.1371/journal.pone.0150990

Table 2. Statin-associated adverse outcomes in Chinese and non-Chinese (referent).

Number of Events (rate per 10,000 person-years) Hazard Ratio (95% CI) P-value
Chinese (n = 19,033) Non-Chinese (n = 57,099)
Rhabdomyolysis * 16 (6.6) 79 (12.8) 0.61 (0.28 to 1.34) 0.22
Incident diabetes 182 (267.5) 475 (252.4) 1.02 (0.80 to 1.30) 0.89
Acute kidney injury * 215 (89.2) 556 (90.8) 0.90 (0.72 to 1.13) 0.36
All-cause mortality 324 (133.5) 965 (156.4) 0.88 (0.74 to 1.05) 0.17

Abbreviations: confidence interval (CI)

* Outcomes assessed with hospital diagnosis codes. This underestimates the true event rate because these codes have high specificity but low sensitivity.

† Diabetes diagnoses assessed with the Ontario Diabetes Database; only matched sets where none of the users had evidence of baseline diabetes were included in this analysis (6,170 Chinese, 18,510 non-Chinese).

‡ All-cause mortality assessed with vital status field of Registered Persons Database of Ontario.