Table 2. Statin-associated adverse outcomes in Chinese and non-Chinese (referent).
Number of Events (rate per 10,000 person-years) | Hazard Ratio (95% CI) | P-value | ||
---|---|---|---|---|
Chinese (n = 19,033) | Non-Chinese (n = 57,099) | |||
Rhabdomyolysis * | 16 (6.6) | 79 (12.8) | 0.61 (0.28 to 1.34) | 0.22 |
Incident diabetes † | 182 (267.5) | 475 (252.4) | 1.02 (0.80 to 1.30) | 0.89 |
Acute kidney injury * | 215 (89.2) | 556 (90.8) | 0.90 (0.72 to 1.13) | 0.36 |
All-cause mortality ‡ | 324 (133.5) | 965 (156.4) | 0.88 (0.74 to 1.05) | 0.17 |
Abbreviations: confidence interval (CI)
* Outcomes assessed with hospital diagnosis codes. This underestimates the true event rate because these codes have high specificity but low sensitivity.
† Diabetes diagnoses assessed with the Ontario Diabetes Database; only matched sets where none of the users had evidence of baseline diabetes were included in this analysis (6,170 Chinese, 18,510 non-Chinese).
‡ All-cause mortality assessed with vital status field of Registered Persons Database of Ontario.