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. 2016 Mar 8;11(3):e0150640. doi: 10.1371/journal.pone.0150640

Fig 3. SMN protein levels in SMA patient and control whole blood samples.

Fig 3

(A) SMN levels with respect to age in all subjects. (B) SMN protein levels were measured in SMA patients with 2, 3 and 4 copies of SMN2. In patients over 2 months of age, SMN levels were significantly greater in SMA patient samples with 4 SMN2 copies relative to those with 2 and 3 SMN2 copies (p = 0.0001). (C) SMN was also measured in three control samples and SMN levels were found to be significantly greater in the control samples relative to levels in SMA patients over 2 months of age (p < 0.0001).