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. 2016 Mar 8;11(3):e0151026. doi: 10.1371/journal.pone.0151026

Fig 3. 8-oxoG, MUTYH and PARP-1 are increased in frataxin knockdown BV2 cells.

Fig 3

(A) 8-oxoG was labeled in BV2 cell culture. BV2 cells treated with frataxin siRNA have more 8-oxoG immunoreactivity compared to BV2 cells treated with control siRNA. Data are expressed as mean± s.e.m. (t test, ** p < 0.01, n = 3) (B) Western-blot of MUTYH and PARP-1 in BV2 cells showed that BV2 cells treated with frataxin siRNAs (siR5, siR6 and siR7) expressed more MUTYH and PARP-1 compared to BV2 cells treated with control siRNA. Data are expressed as mean± s.e.m. (one way ANOVA, ** p < 0.01, *** p<0.001, n = 3).